The wisdom of using aftertouch to control the Leslie is dependent on how realistic you want to be. If you're going for realism, then aftertouch wouldn't work well. When using a Leslie speaker, players would turn it on and off, not tweak the rotation speed while playing. A foot switch would do this far better than aftertouch.
On the other hand, if you're trying to go beyond realism, then using channel aftertouch could be interesting. However, when releasing all of the keys, the leslie would drop to zero even if the sound hasn't ended yet. This may be what you're looking for, but realistic it's not.
The use of polyphonic aftertouch to control a leslie effect may not be feasible. Most leslie effects I know are located after all the individual key sounds are summed together. As such, I'm not at all sure which key's pressure would affect the speed. On the other hand, if the leslie effect was part of the sound prior to the keys being summed, then you could theoretically have one note only going through the leslie. or each note at a different rotational speed. This could be a very interesting sound, but it definitely throws realism away.